Luca Moretti

This is my community; I analyze everything with complete objectivity. Here, you’ll find news and methods for making money with AI, and...
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Luca MorettiProfile picture@lucamoretti99·16h

My goal is to post content daily and be available to members 24/7; I am currently trying to document at least 1% of what I know—knowledge that represents 99% of what isn't shared publicly.


My aim with this community is for you to build friendships and make money—first individually, then together—and to grow into much larger, more prosperous groups.

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Luca MorettiProfile picture@lucamoretti99·16h

Do you know the most-watched show on the planet?


Joe Rogan has spoken with approximately 1,200 people across 2,560 episodes, likely covering every conceivable human category. I will teach you how to create bots that embody the person in question—using all their accumulated knowledge to respond to you exactly as that person would.


This applies to anyone with online or physical content (whether they’ve made videos or written books).

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Luca MorettiProfile picture@lucamoretti99·19h

We can say that today, October 12th, marks the start of our daily posting schedule and the growth of this community.


I will soon release:


  • a trading bot, once I am certain it generates a 100% profit rate;

  • a sports betting bot, once it consistently makes money for me 7 days a week;

  • a "mastermind" bot to control other bots—like Dots, GrokBot, or Muse—but open-source so you can customize it however you like; it runs everything from a single PC (let's call it "Jarvis Junior").


I believe Jarvis Junior is capable of posting across all social media channels, sending emails, and posting on forums—performing all these actions simultaneously.


Give me a week to get everything sorted, and they’ll be yours.


+ I’m going to turn this community into a place where you’ll spend at least two hours a day; I’ll also be putting a lot of work into the entertainment side of things.

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Luca MorettiProfile picture@lucamoretti99·21h

The first ER-100 human trial: are we reprogramming cells to turn back the aging clock?


The question Elon Musk posed at Davos—"can aging be reversed?"—received an unexpected answer: "Clinical trials are starting soon." This announcement came from Harvard professor David Sinclair on X, confirming that ER-100 had received the green light from the FDA. It is not a supplement, nor is it a study on mice. It is the first-ever human clinical trial for epigenetic reprogramming.


What is ER-100? A gene therapy from Life Biosciences (Boston). It does not alter existing genes; instead, it uses an AAV2 vector to deliver instructions for three proteins—OCT4, SOX2, and KLF4 ("OSK")—which are three of the Yamanaka factors (associated with the 2006 Nobel Prize). The mechanism is clever: the genes activate only while the patient takes doxycycline (for 8 weeks) and then switch off. It is a "partial reset" with a built-in brake.


Why the eye? Retinal ganglion cells do not regenerate naturally; vision lost to glaucoma is generally permanent. The eye is also a closed system, so injecting into just one eye limits the risks.


What the data show (AAO 2026): 3 patients received the initial dose; zero serious adverse events were reported by day 56; 2 out of 3 showed improved visual fields (≥28% of points, +4 dB); and the DSMB approved escalating the dose to 6×10¹¹ vg (a threefold increase). What it does NOT demonstrate: 3 patients, open-label study, 56 days—it is a signal, not a verdict. It is not whole-body rejuvenation. Reprogramming caused tumors in animals; OSK activates hundreds of genes. As for Sinclair, the WSJ (2024) described his companies as having "no results." The best-case scenario: "it resolves blindness for some and catalyzes other indications—it’s not as if a doctor would prescribe you a rejuvenation pill."


What’s next: an active trial (NCT07290244), 18 patients (12 with glaucoma + 6 with NAION), 4 US sites, 5-year follow-up, estimated completion in 2032.